Insurance: If you plan to use insurance, make sure the online provider accepts it. These small differences affect the way each medication works, such as how quickly it takes effect and wears off, and the possible side effects. A higher dose of tadalafil is needed if your body does not respond to the recommended dose. Never purchase ED medications from a site or service that doesn’t require a prescription and medical documentation. Avanafil Stendra. We also looked at additional services, such as access to digital pharmacies and home delivery options.Most user-friendly Hims Cialis (3+) from Hims Delivery time: 2–5 business days Prescription needed: yes Accepts insurance: no Dosage: 5 mg SHOP NOW AT HIMS Healthline ‘s review Hims is. Cialis and generic tadalafil are available with a prescription only. There is no OTC version, though there have been efforts in recent years to develop a nonprescription version of tadalafil. tadalafil. erectile dysfunction (ED) benign prostatic hyperplasia, or BPH). Tadalafil (Cialis) is available both as brand-name and generic tablets. Common side effects of this medication include headache and indigestion. Tadalafil (Cialis) does interact with some medications.