Daily doses are often between 2. It may take some time and trial and error to determine the best dosage as well as the best time to take Cialis. When taken at the correct time and paired with sexual stimulation, the erection lasts long enough for successful intercourse. We considered cost, medications available, and whether generic versions were offered to help reduce costs. The medication should be taken once daily at about the same time every day to maintain a consistent level of medicine in the body.If you’ve ever looked into getting a medication for erectile dysfunction (ED), you may know that treatment prices can vary. Cialis (tadalafil), for instance, is one of the most popular . Tadalafil, or generic Cialis, is most commonly used to treat erectile dysfunction (ED). However, it’s also used to treat benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension.  · But on average, its effects start to lessen 2 to 3 hours after you take a dose. The typical dose for once-daily Cialis for ED is milligrams (mg) to 5 mg. When used as needed for ED, the usual.