How Effective Is Cialis? Cialis is a brand-name prescription medication. Read it again each time you refill your prescription in case there is new information. The results showed the combination to be even more effective than either medication alone. The enlarged prostate interferes with the normal flow of urine from the bladder and urinary tract, resulting in lower urinary tract symptoms, such as trouble urinating. From Mayo Clinic to your inbox Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Take both tablets at the same time each day.Pay undefined at Walgreens with a GoodRx discount. That’s 62% off the retail price of $ Walgreens. $ retail. Save 62% $ chevron_right. Get free savings. Most popular. Lowest price. Pay undefined at CVS Pharmacy with a GoodRx discount. That’s 26% off the retail price of $ CVS Pharmacy. $ retail. Save 26%.  · Expert-reviewed resources to help you navigate your health journey, from A to Z and everything in between. Compare prescription drug prices and find coupons at more than 70, US pharmacies. Save up to 80% instantly!  · For treatment of pulmonary arterial hypertension: Adults—40 milligrams (mg) (two 20 mg tablets) taken once a day. Take both tablets at the same time each day. Do not divide the 40 mg dose. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.