FDB Multilex and those who are responsible for their construction, operation and maintenance do not know the particular circumstances, condition or medical history of particular patients or groups of patients and so cannot advise as to particular cases. Dosage, administration, and formulation Oral dapoxetine is indicated for the treatment of men aged 18—64 years with premature ejaculation. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines. Manufacturer advises avoid with concurrent use of potent inhibitors of CYP3A4 except in patients verified to be extensive CYP2D6 metabolisers where manufacturer recommends max. This is so your doctor can check on your progress. Dapoxetine is a short-acting selective serotonin re-uptake inhibitor.Dapoxetine is prescribed for the treatment of premature ejaculation. Take one tablet hours before you have sex. The most common side-effects include feeling dizzy or faint, and feeling sick (nausea). Drinking a full glass of water at the same time as taking the tablet can reduce these effects. Dapoxetine is a selective serotonin transport inhibitor with unique pharmacokinetic and pharmocodynamic properties that account for its clinical effects. Future studies may demonstrate whether dapoxetine could possess many of the attributes of an ideal compound for the treatment of PE. Dapoxetine is a selective serotonin reuptake inhibitor, structurally related to fluoxetine, which was initially being developed by Eli Lilly for the potential treatment of depression, for which it was in phase I trials; however, no development regarding this indication has been reported after