Your healthcare provider can help you determine the right dosage for you. In such circumstances, nitrates should still only be administered under close medical supervision with appropriate hemodynamic monitoring. It comes as tablets. Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy NAION , a rare condition and a cause of decreased vision, including permanent loss of vision, that has been reported rarely postmarketing in temporal association with the use of all PDE5 inhibitors. Cialis: Is one right for you? In those patients already taking an optimized dose of PDE5 inhibitor, alpha-blocker therapy should be initiated at the lowest dose.シアリスの成分「タダラフィル」の効果. 陰茎の海綿体には多くのPDE-5（5型ホスホジエステラーゼ）が存在していますが、通常時に勃起していないのはこのPDE-5の働きによるものです。. しかし、何らかの原因でPDE-5が増え過ぎると、勃起したいときにでき. Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Was this helpful? How does Cialis work? Cialis works by increasing blood flow to the penis to help a person get and maintain an erection. It also blocks the PDE5 .